Anatomically aware simulation of patient-specific glioblastoma xenografts
Malik et al. · PLoS Comput Biol · 2026-01-20
基于小鼠脑解剖的患者特异性GBM异种移植生长/侵袭模型；ABC拟合；通过扰动参数模拟治疗。
标签：临床前
共 3 条，按时间倒序。
AI-driven virtual cell models in preclinical research: technical pathways, validation mechanisms, and clinical translation potential.
Ma C, Zhang H, Rao Y, Jiang X, Liu B, Sun Z, Song Z, Gao Y, Cui Y, Liu X, Li Z. · NPJ digital medicine · 2025-12-11
综述：AI虚拟细胞在临床前研究中的技术路径与验证机制。
In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma.
Liu SJ et al. · Genome biology · 2024-10-07
GBM体内Perturb-seq：解析驱动基因与放疗反应——脑肿瘤虚拟细胞的关键训练数据类型。