Anatomically aware simulation of patient-specific glioblastoma xenografts
Malik et al. · PLoS Comput Biol · 2026-01-20
Patient-specific GBM xenograft growth/invasion model on mouse brain anatomy; ABC fit; treatment via parameter perturbation.
Tag: Preclinical
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AI-driven virtual cell models in preclinical research: technical pathways, validation mechanisms, and clinical translation potential.
Ma C, Zhang H, Rao Y, Jiang X, Liu B, Sun Z, Song Z, Gao Y, Cui Y, Liu X, Li Z. · NPJ digital medicine · 2025-12-11
Review of AI virtual cell models in preclinical research: technical pathways and validation.
In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma.
Liu SJ et al. · Genome biology · 2024-10-07
In vivo Perturb-seq of GBM and microenvironment dissects drivers and radiotherapy responses.