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Hara T et al. · Cancer cell · 2025-05-27
Hara et al.: immune–cancer interactions drive MES-like transitions in GBM.
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preprintBrain tumor✓ VerifiedVC0093
Kint S et al. · bioRxiv · 2025-05-14
Spatial epigenomic niches underlie GBM cell-state plasticity.
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paperBrain tumor✓ VerifiedVC0059
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Neftel et al.: four GBM malignant states (NPC/OPC/AC/MES), plasticity and genetics.
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preprint✓ VerifiedVC0139
Metzner E, Guruvayurappan K, Southard KM, Ardy RC, Dey KK, Norman TM. · bioRxiv · 2026-10-12
Norman/Dey labs (MSKCC): CRISPRa Multiome Perturb-seq of 119 TFs + dual-guide Perturb-seq of 1,225 TF pairs in RPE-1; chromatin priming predicts emergent states; Mosaic (Transformer) predicts TF-pair interaction residuals (r=0.484) and nominated a validated triple-TF combination.
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paperBrain tumor✓ VerifiedVC0096
Melhem A et al. · Nature protocols · 2026-07-28
Core2Edge: GBM organoid-brain slice infiltration model (Nat Protoc).
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paperBrain tumor✓ VerifiedVC0097
Jungwirth G et al. · NPJ precision oncology · 2026-06-16
Automated personalized GBM organoid drug screening platform.
DOIPubMed