Methods & evidence policy
Sources
Papers and preprints are verified against PubMed, Europe PMC or Crossref; models, datasets, news and conferences against their official pages. Each library item records its verification source. Key claims on topic pages are checked against the article abstract (Europe PMC) where available.
Evidence grading
Evidence is labelled descriptively rather than scored:
- Peer-reviewed primary study — original data, published in a journal.
- Preprint — not peer reviewed; always marked “preprint”.
- Model system — cell lines, organoids, xenografts or mouse models; stated explicitly because results may not transfer to patients.
- Computational only — no experimental or clinical validation.
- Benchmark / critique — independent tests of claims; included alongside positive results.
- Clinical validation — prospective evidence in patients. None of the virtual-cell items in the library currently reach this level.
Topic pages and the knowledge graph
Each topic page is generated from a JSON record in content/graph/ listing questions, entities, evidence (library IDs), related topics and an explicit uncertainties section. The build fails if a citation is not in the library, if a related topic does not exist, or if the uncertainties section is missing.
Review policy
Pages start as draft with status “Review pending” and lastReviewed empty. A page is marked reviewed only after the editorial team has read it against the cited sources; the version number increases with each substantive change. Clinical commentary is written by the editorial team and labelled.
Update cadence
The library is updated weekly. Topic pages show their version and last-updated date; corrections are welcome.
No patient data
GlioState contains no patient data, no clinical case reports and no identifiable information. It only summarises published or publicly posted sources. The site uses no trackers or cookies.
For research and education only. Not medical advice and not a recommendation of any diagnosis, treatment or product. Patients should consult their own physicians.