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xenografts","year":"2026","page_url":"https://gliostate.com/library/VC0133/","api_url":"https://gliostate.com/api/items/VC0133.json"}],"mentioned_in_topics":[{"id":"cell-state-mes-like","title_en":"Mesenchymal-like (MES-like) glioblastoma cell state","title_zh":"胶质母细胞瘤间充质样（MES 样）细胞状态","url":"https://gliostate.com/cell-states/mesenchymal-like/","api_url":"https://gliostate.com/api/topics/cell-state-mes-like.json"},{"id":"cell-state-npc-opc-like","title_en":"Neural-progenitor-like (NPC-like) and OPC-like glioma cell states","title_zh":"神经前体样（NPC 样）与少突前体样（OPC 样）胶质瘤细胞状态","url":"https://gliostate.com/cell-states/neural-progenitor-like-opc-like/","api_url":"https://gliostate.com/api/topics/cell-state-npc-opc-like.json"},{"id":"dataset-gbm-single-cell-spatial","title_en":"Glioblastoma single-cell and spatial datasets","title_zh":"胶质母细胞瘤单细胞与空间数据集","url":"https://gliostate.com/datasets/gbm-single-cell-spatial/","api_url":"https://gliostate.com/api/topics/dataset-gbm-single-cell-spatial.json"},{"id":"model-virtual-cell","title_en":"AI virtual cell models","title_zh":"AI 虚拟细胞模型","url":"https://gliostate.com/models/virtual-cell/","api_url":"https://gliostate.com/api/topics/model-virtual-cell.json"},{"id":"perturbation-gbm-therapy","title_en":"Perturbation data for glioblastoma: radiotherapy, drugs and CRISPR","title_zh":"胶质母细胞瘤扰动数据：放疗、药物与 CRISPR","url":"https://gliostate.com/perturbations/gbm-therapy-perturbations/","api_url":"https://gliostate.com/api/topics/perturbation-gbm-therapy.json"},{"id":"transition-therapy-induced-plasticity","title_en":"Therapy-induced plasticity in glioblastoma","title_zh":"胶质母细胞瘤的治疗诱导可塑性","url":"https://gliostate.com/transitions/therapy-induced-plasticity/","api_url":"https://gliostate.com/api/topics/transition-therapy-induced-plasticity.json"},{"id":"validation-gbm-state-replication","title_en":"Do Neftel-style GBM state calls replicate across platforms? 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hypoxia coordinates myeloid-cell spatial organisation.","zh":"缺氧依赖的生态位与不良预后相关（GBmap）；缺氧协调髓系细胞的空间分布。"},"sources":[{"kind":"topic","id":"dataset-gbm-single-cell-spatial","url":"https://gliostate.com/datasets/gbm-single-cell-spatial/","api_url":"https://gliostate.com/api/topics/dataset-gbm-single-cell-spatial.json"}]}],"related_entities":[{"id":"glial-progenitor-like-state","type":"cell_state","name_en":"Glial-progenitor-like cells","name_zh":"胶质祖细胞样细胞","page_url":"https://gliostate.com/entities/glial-progenitor-like-state/","page_url_zh":"https://gliostate.com/zh/entities/glial-progenitor-like-state/","api_url":"https://gliostate.com/api/entities/glial-progenitor-like-state.json","via":"relation"},{"id":"gbmap","type":"dataset","name_en":"GBmap","name_zh":"GBmap","page_url":"https://gliostate.com/entities/gbmap/","page_url_zh":"https://gliostate.com/zh/entities/gbmap/","api_url":"https://gliostate.com/api/entities/gbmap.json","via":"relation"},{"id":"gbm-organoid-biobank","type":"dataset","name_en":"Patient-derived GBM organoid biobank","name_zh":"患者来源 GBM 类器官生物库","page_url":"https://gliostate.com/entities/gbm-organoid-biobank/","page_url_zh":"https://gliostate.com/zh/entities/gbm-organoid-biobank/","api_url":"https://gliostate.com/api/entities/gbm-organoid-biobank.json","via":"relation"},{"id":"scfocal","type":"model","name_en":"scFOCAL / ISOSCELES","name_zh":"scFOCAL / ISOSCELES","page_url":"https://gliostate.com/entities/scfocal/","page_url_zh":"https://gliostate.com/zh/entities/scfocal/","api_url":"https://gliostate.com/api/entities/scfocal.json","via":"relation"},{"id":"perturb-seq","type":"method","name_en":"Perturb-seq","name_zh":"Perturb-seq（扰动单细胞测序）","page_url":"https://gliostate.com/entities/perturb-seq/","page_url_zh":"https://gliostate.com/zh/entities/perturb-seq/","api_url":"https://gliostate.com/api/entities/perturb-seq.json","via":"relation"},{"id":"hypoxia","type":"pathway","name_en":"Hypoxia","name_zh":"缺氧","page_url":"https://gliostate.com/entities/hypoxia/","page_url_zh":"https://gliostate.com/zh/entities/hypoxia/","api_url":"https://gliostate.com/api/entities/hypoxia.json","via":"relation"},{"id":"neftel-four-state-framework","type":"method","name_en":"Neftel four-state framework","name_zh":"Neftel 四状态框架","page_url":"https://gliostate.com/entities/neftel-four-state-framework/","page_url_zh":"https://gliostate.com/zh/entities/neftel-four-state-framework/","api_url":"https://gliostate.com/api/entities/neftel-four-state-framework.json","via":"co-mention"},{"id":"mes-like-state","type":"cell_state","name_en":"Mesenchymal-like (MES-like) state","name_zh":"间充质样（MES 样）状态","page_url":"https://gliostate.com/entities/mes-like-state/","page_url_zh":"https://gliostate.com/zh/entities/mes-like-state/","api_url":"https://gliostate.com/api/entities/mes-like-state.json","via":"co-mention"}]}